LRRIQ1 (англ. Leucine rich repeats and IQ motif containing 1) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 12-ї хромосоми. Довжина поліпептидного ланцюга білка становить 1 722 амінокислот, а молекулярна маса — 199 300.
Послідовність амінокислот
| 10 |
|
20 |
|
30 |
|
40 |
|
50 |
| MDDDDAKLKA |
|
EIEAELDKLS |
|
ISSLEKEDIE |
|
SDAKSETQSD |
|
DSDTDSVELP |
| ESVLHCINII |
|
KNRSKAVEEL |
|
ILQDLEDTDI |
|
LSCSYGAVSN |
|
NHMHLRTGLS |
| TEYEESSEQL |
|
IKILSEIEKE |
|
EFMRSKTDCA |
|
TPDFVPEPSP |
|
HDLPMDEHVL |
| PDDADINFGY |
|
CEVEEKCRQS |
|
FEAWQEKQKE |
|
LEDKEKQTLK |
|
AQRDREEKQF |
| QEEEEKRHCW |
|
MKQFKVEKKK |
|
LENIQKQEQD |
|
KMNDELYKEE |
|
KIWKEKFKQH |
| EEYIRNLHLQ |
|
MEEERTRFKD |
|
QQEKEKNSLL |
|
KQQNNAAVKI |
|
QAKYKAFVAY |
| QKYGPIIKEQ |
|
IESKKRKAQE |
|
WKEKEAKIRQ |
|
KEEENRKRLE |
|
EEQRIKEERK |
| KQKEEERKRR |
|
EKEYEEKKNI |
|
VKQEREQLIS |
|
KEKIILREDA |
|
SQQLIISSAL |
| KKSGYNNKHL |
|
SLEDISNDKG |
|
DIAKNLVDEN |
|
SKKQEDVLLW |
|
LVEESNMKEN |
| VDRQTILKES |
|
IQVKLKESIS |
|
SQTILADFKM |
|
EEKNENLAKK |
|
RCSEELVKQE |
| RKYENTDNKT |
|
ELGNSDLKGN |
|
LKEQFPLQEL |
|
KSDAQKEEKI |
|
MKHVINENTG |
| QKTQIILGHN |
|
QEISEVKTNE |
|
EQKIIKDNQQ |
|
KKIQKVEKEE |
|
IQEQNGLLYK |
| DKDTLVISVK |
|
QRSLSLTSEN |
|
SKDVRENVIL |
|
QEKEIYSKSK |
|
EIEENPKDNA |
| WNSGIVIFNT |
|
TDTMINIEGK |
|
RNDQDYVLGR |
|
HAPCEGLSNY |
|
NAESSMVSKE |
| VNSLKSEIRN |
|
ISEKCHENAP |
|
EPDSMTCCVS |
|
ESTLLYSIEE |
|
RRLAWIKSFK |
| PWLEIFKQNQ |
|
QKKIVRRKRP |
|
VKCPANMTPA |
|
LDKLEILRCG |
|
PWDTLQQVTT |
| VTFQDLPGCV |
|
LSTLAECTNL |
|
QFLSLRRCGL |
|
TSLHSLSNCK |
|
KLKYIDAQEN |
| HIEAIECENL |
|
ENLCVVLLNK |
|
NQLTSLHGLD |
|
GCTNIQCLEL |
|
SYNKITRIGY |
| SFFLEEKLVD |
|
NAGFCHHLGT |
|
STSYLSLAQV |
|
WIPTGLCWSW |
|
IPITSLTKNS |
| DCNFLISHLY |
|
WNCGLESLKN |
|
LQQLILDHNQ |
|
LINTKGLCDT |
|
PTIVYLDCSH |
| NHLTDVEGVE |
|
NCGLLQILKL |
|
QGNYLSELPS |
|
LENLVLLREL |
|
HLDDNSISTV |
| EAFSSYWLPL |
|
LQNITISQNS |
|
LTKIVPLFHF |
|
VSLEKLDVSH |
|
NCLSDLKSAI |
| KWFDACYSLH |
|
ELSLTGNPLL |
|
QETNWRDSLL |
|
KVLPALRILN |
|
GNILNSNSES |
| RTEEHNQLGS |
|
AGFLALCQSQ |
|
IREFNLLIEN |
|
YITGKGDVFT |
|
LDTAENLCHY |
| FKKLMILSTE |
|
YRHAHERGDV |
|
TITKKDESEA |
|
QKNHLAPTNS |
|
DSTLQNGVFY |
| SCAREGEPDS |
|
PDIPEKWMDS |
|
VSSHSPLSKS |
|
ATCENMEGRH |
|
QEILVCQKRE |
| DSKASSIPTI |
|
RIPFKEVVMT |
|
NSLLRNHQNI |
|
EPSEKIMAAV |
|
VIQSYWRGYL |
| MRRQTHFSTR |
|
LHTAATEGLP |
|
NSSIKNQTIL |
|
KKGKRENIVN |
|
IRKQREKAAI |
| LIQAVWKGFI |
|
LRKKLTTALE |
|
AIKNEESDEE |
|
YREIDLEDFI |
|
FDEAALEEEW |
| LALDSTRFPS |
|
QTLLLSNQLH |
|
WPKIPGNLKW |
|
DDTSFNLPSN |
|
PAQAWLCNDK |
| ENLSSSEHTQ |
|
FNSRSENKTS |
|
SWTPESKTSR |
|
KSLLKSEKEK |
|
KISEEWGFKD |
| ISTAQQMLKR |
|
AQKMKSKKLK |
|
KKIDSTVRLA |
|
LFKNNENKVS |
|
LPKSPKMVQP |
| RRDGYFEGIE |
|
EDPIHKDTTA |
|
NEKLERNREY |
|
TYQWLHTQVG |
|
VHETTSSRNM |
| KCNHFLPELD |
|
PDVLNGGRVQ |
|
LVARLVSRED |
|
TDLDLFSMTN |
|
GSALSVNREK |
| KNQAHRHSAG |
|
SSSKLWFPSK |
|
LI |
Задіяний у такому біологічному процесі, як альтернативний сплайсинг.
Література
-
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res. 14: 2121 — 2127. 2004. PubMed DOI:10.1101/gr.2596504
-
Nagase T., Nakayama M., Nakajima D., Kikuno R., Ohara O. (2001). Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.. DNA Res. 8: 85 — 95. PubMed DOI:10.1093/dnares/8.2.85
Див. також
